Skull art tattoos symbolize the transience of life, mortality, and the inevitability of death, serving as a reminder to live life to the fullest. They can also represent rebellion, nonconformity, and a rejection of mainstream values, signifying a person's willingness to challenge societal norms. Additionally, skull tattoos can be a symbol of transformation, renewal, and spiritual growth, signifying a person's ability to confront and overcome adversity.